Notable Cambodian-American
- Andrew Chanbunna Taing - Lawyer
- Arn Chorn-Pond - Musician and Human Rights Activist
- Bhante Dharmawara - Buddhist monk and teacher who helped resettle millions of Cambodian refugees in the US and who founded the first Cambodian Buddhist temple in the US
- Bonna Tek - Actress
- Chom Nimul - Singer
- Dr. Channy Sak Humphry - Khmer language professor at University of Hawaii
- Chanthou Oeur - Painter and sculptor
- Chath PierSath - Poet, painter and humanitarian
- Dr. Chet Chea - Medical Doctor
- Chhun Yasith - Political activist
- Danny Narong Chum - Lawyer
- Dith Pran (b. 1942) - Photojournalist for the New York Times, Human Rights Activist
- Dr. Elizabeth Chea - Medical Doctor
- Dr. Erica Sok - Dentist
- Dr. Gaffar Peang-Meth - retired Political Science professor at University of Guam.
- Haing S. Ngor - Oscar-winning actor, author, physician
- Hong Net - Third Cambodian-American elected Lynn City Council in 2012.
- Koke Lor - sexy Apsara artist, Chicago Art Institute
- Kris Dim - Pro bodybuilder, Los Angeles, CA.
- Lian Cheun - http://www.presstelegram.com/government-and-politics/20140606/khmer-girls-in-action-leader-lian-cheun-joins-white-house-commission-on-asian-americans#
- Loung Ung - Author, speaker, Khmer Rouge survivor and activist against landmines
- Maddox Chivan Jolie-Pitt - Adopted son of actors Angelina Jolie and Brad Pitt
- Judge Meng Hong Lim - The first Cambodian-American ever elected to Superior Court Judge in Georgia, USA in 2015
- Dr. Mey Sokharith - Medical Doctor
- Monirith Chhea - Artist originally from Phnom Penh
- Mu Sochua - Human Rights Activist and Politician
- Narath Tan - Sculptor and artist
- Phaen Morn - Lawyer
- Dr. Phalla Chea - Lowell Public School Leisure
- Dr. Phalla Kith - Medical Doctor
- Porthira Chhim - Author
- Pou Sohtireak - Politician[8]
- Rady Mom - First Cambodian-American elected US State Representative in Lowell, MA. 2015
- Dr. Ritha Chea - Internal Medicine
- Rithy Uong - First Cambodian-American elected Lowell City Council in 2000.
- Sam-Ang Sam - Ethnomusicologist and MacArthur Fellow
- Sam Meas - First Cambodian-American congressional candidate.
- Samnang Mam - Lawyer
- Dr. Samrang K. Kchao - Medical Doctor
- Dr. Sengly Kong - Public Policy Analysis
- Dr. Serena Chuop - Dentist
- Sichan Siv - former U.S. Ambassador to the United Nations Economic and Social Council
- Siemny Kim - Cambodian-American TV Anchor/Reporter in 2015.
- Soben Huon - Miss Utah USA 2006. Miss USA competitor.
- Somaly Mam - Author and Human Rights Advocate
- Sophiline Cheam Shapiro - choreographer and dance teacher[7] noted Cambodian classical music performer[1]
- Sucheng Chan - Author
- Ted Ngoy - The "Doughnut King," entrepreneur and politician
- Theary Seng - Lawyer and Human Rights Activist
- Tim Thou - Founder of Angkor Dance Troupe, Lowell, Ma.
- Vesna Nuon - Second Cambodian-American elected Lowell City Council in 2012.
- Virginia Prak - Miss Cambodian-American pageant won 2nd place in Miss Global in Philippine in 2015.
- Vichet Sum - Professor at University of Maryland
- Yary Livan - Master ceramicist and artist